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This innovative form of folate (5-MTHF) has demonstrated high bioavailability, solubility, and long-lasting stability ideal for supplementation.* Mechanism of Action Methylation Support* The ingredients in Ultra B12-Folate support methylation reactions that provide critical functions to promote normal DNA synthesis and repair, cellular energy metabolism, nerve cell structure and function, and red blood cell production

Improving the transfection efficiency of post-mitotic neurons

Having a metabolic disease such as obesity or type 2 diabetes, as well as a low-choline, methionine, or inositol diet, can make weight loss difficult

Indications Reconstitution of lyophilized powders for injection (e.g., hormones, peptides) Dilution of injectable medications Used in intramuscular, subcutaneous, or intravenous routes as directed by medication instructions Dosage and Administration Dosage determined by the medication being reconstituted or diluted For parenteral use only Use a sterile needle and syringe when accessing the vial After first use, discard unused portion after 28 days Do not use if solution is discolored, cloudy, or contains particulates Contraindications Neonates (newborns), due to risk of gasping syndrome caused by benzyl alcohol Known hypersensitivity to benzyl alcohol or any component of the solution Precautions Use with caution in pregnant or breastfeeding women Caution in patients with hepatic or renal impairment Use only with medications compatible with bacteriostatic water Not for use as a standalone injection without a compatible solute Possible Side Effects Local injection site irritation or inflammation Allergic reactions: rash, itching, facial swelling, trouble breathing (rare) Benzyl alcohol toxicity in sensitive populations (especially neonates) Drug Interactions Bacteriostatic Water itself has no pharmacologic interaction

Others describe difficulty sleeping, particularly with late-day injections